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Advanced breast cancer means that a cancer that began in the breast has spread to another part of the body. It might not mean that you have advanced cancer if you have the symptoms described below. Advanced breast cancer means that a breast cancer has spread to another part of the body. It doesnt include breast cancers that are affecting the lymph glands under the arm. Or the cancer has come back and spread after treatment for the original. When you find out you have advanced breast cancer, called metastatic or stage iv cancer, you probably have a lot of questions. What is locally advanced breast cancer? Locally advanced breast cancer is invasive breast cancer that has one or more of the following features may be large (typically bigger than 5 cm) may have spread to several lymph nodes in the armpit (axilla) or other areas near the breast may have spread to other tissues around the breast such as the skin, muscle or ribs. Locally advanced cancer is used to describe cancer that has grown outside the organ it started in but has not yet spread to distant parts of the body. For instance, breast cancer that has spread to the lungs is called metastatic breast cancer to the lungs its not lung cancer. Treatment for advanced breast cancer can often shrink the cancer or slow its growth (sometimes for many years), but after a time, it tends to stop working. Further treatment options at this point depend on several factors, including previous treatments, where the cancer is located, and a womans. stage 4 breast cancer, also called metastatic breast cancer, is considered the most advanced stage. The eso-esmo 4th international consensus guidelines for advanced breast cancer (abc 4) focus on methodology, assessment guidelines and treatment recommendations for specific breast cancer subtypes including er positiveher2-negative (luminal) abc, her2-positive abc, triple-negative abc and male metastatic breast cancer, as well as patients with specific metastases. however, when breast cancer is not picked up early and given the chance to spread - known as advanced - it becomes incurable. It can most commonly spread to the bones, brain, lungs or liver.